翁海波,博士,教授,一直从事分子生物学和基因工程相关研究工作,参与和主持多项国家级和省级科研项目,已发表多篇SCI论文。
研究方向:
1)基因工程与发酵工程
2)癌症发病机制与检测
目前在研科研项目:
1)国家自然科学基金面上项目:4.1N与EGFR作用抑制乳腺癌发生和去分化的机制研究,2015-2018
2)河南省科技攻关项目:表达胸腺肽α1枯草杆菌在畜禽饲中的应用,2014-2016
近年已发表SCI论文:
1)Weng H, Guo X, Papoin J, Wang J, Coppel R, Mohandas N, An X*. Interaction of Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) with erythrocyte ankyrin R is required for its attachment to the erythrocyte membrane. Biochim Biophys Acta. Biochim Biophys Acta. 2014, 1838(1):185-92. (第一作者)
2)Liu C, Weng H, Chen L, Yang S, Wang H, Debnath G, Guo X, Wu L, Mohandas N, An X. Impaired intestinal calcium absorption in 4.1R-deficient mice due to altered expression of plasma membrane calcium ATPase 1b. J Biol Chem. 2013, 288(16): 11407-15. (第二作者)
3)Yang S,Weng H, Chen L, Guo X, Parra M, Conboy J, Debnath G, Lambert AJ, Peters LL, Baines AJ, Mohandas N, An X. Lack of protein 4.1Gcauses altered expression and localization of the cell adhesion molecule nectin-like4 intestis and can cause male infertility. Mol Cell Biol. 2011, 31(11):2276-86.(第二作者)
4)Yang D,Weng H*, Wang M, Xu W, Li Y, Yang H.. Cloning and Expression of a novel Thermostable Cellulase from newly isolated Bacillus subtilis strain I15. Mol Biol Rep. 2010, 37(4):1923-9.(*通讯作者)
5)You L,Weng H*, Chen Z, Wang A, Xu W, Wang M, Dong Z.. A novel vector for direct cloning PCR fragments by positive selection based on the lethal barnase.Mol Biol Rep.Mol Biol Rep. 2009, 36(7):1793-8. (*通讯作者)
6)Gao J,Weng H*, Xi Y, Zhu D, Han S. Production and characterization of cellulolytic enzymes from the thermoacidophilic fungalAspergillus terreusM11 under solid state cultivation of corn stover. Bioresource Technol. 2008, 99(16):7623-9. (*通讯作者)
7)Gao J,Weng H*, Xi Y, Zhu D, Han S. Purification and characterization of a novel endo-β-1,4-glucanase from the thermoacidophilicAspergillus terreusM11. Biotechnology Letters. 2008, 30(2):323-7.(*通讯作者)