近五年 主要成果
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一、 代表性论文(第一作者或通讯作者) 1. Molecular Characterization of the ORF3 and S1 Genes of Porcine Epidemic Diarrhea Virus Non S-INDEL Strains in Seven Regions of China, 2015. PLoS One. 2016,11(8):e0160561.
2. Epidemiological investigation reveals genetic diversity and high co-infection rate of canine bocavirus strains circulating in Heilongjiang province, Northeast China. Res Vet Sci. 2016, 106:7-13.
3. Co-Circulation of Canine Coronavirus I and IIa/b with High Prevalence and Genetic Diversity in Heilongjiang Province, Northeast China. PLoS One. 2016, 11(1):e0146975.
4. A recombinant nucleocapsid protein-based indirect enzyme-linked immunosorbent assay to detect antibodies against porcine deltacoronavirus. J Vet Med Sci. 2015 Dec 13. [Epub ahead of print] PubMed PMID: 26668175.
5. Epidemiology and vaccine of porcine epidemic diarrhea virus in China: a mini-review. J Vet Med Sci. 2015 Nov 3. [Epub ahead of print] PubMed PMID: 26537549.
6. Co-Circulation of the Rare CPV-2c with Unique Gln370Arg Substitution, New CPV-2b with Unique Thr440Ala Substitution, and New CPV-2a with High Prevalence and Variation in Heilongjiang Province, Northeast China. PloS One. 2015 Sep 8;10(9):e0137288.
7. Prevalence and phylogenetic analysis of canine kobuviruses in diarrhoetic dogs in northeast China. J Vet Med Sci. 2015 Aug 7. [Epub ahead of print] PubMed PMID:26256044.
8. Analysis of protein expression changes of the Vero E6 cells infected with classic PEDV strain CV777 by using quantitative proteomic technique. J Virol Methods, 2015, pii: S0166-0934(15)00069-5.
9. Effects of Selenium Deficiency on Principal Indexes of Chicken Kidney Function. Biol Trace Elem Res. 2015, 164(1):58-63.
10. Shotgun Proteomic Analysis of Plasma from Dairy Cattle Suffering from Footrot: Characterization of Potential Disease-Associated Factors. PLoS ONE, 2013, 8(2): e55973.
11. Proteomic Analysis of Membrane Proteins of Vero Cells: Exploration of Potential Proteins Responsible for Virus Entry. DNA and Cell Biology, 2014, 33(1):20-8.
12. Screening and antiviral analysis of phages that display peptides with an affinity to subunit C of porcine aminopeptidase. Monoclon Antib Immunodiagn Immunother. 2013, 32(5):326-9.
13. Expression and Purification of the scFv from hybridoma cells secreting a monoclonal antibody against S protein of PEDV. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2013, 32(1): 41-46.
14. Identification of a 43-kDa outer membrane protein of Fusobacterium necrophorum that exhibits similarity with pore-forming proteins of other Fusobacterium species. Research in Veterinary Sciences. 2013, 95: 27-33.
15. Preparation of monoclonal antibodies against bovine haptoglobin. Monoclon Antib Immunodiagn Immunother. 2014, 33(5):350-3.
16. A polyclonal antibody against recombinant bovine haptoglobin expressed in Escherichia coli. Monoclon Antib Immunodiagn Immunother. 2013, 32(6):419-24.
17. Identification of two novel B cell epitopes on porcine epidemic diarrhea virus spike protein. Vet Microbiol. 2008, 131(1-2):73-81.
18. Metal-Binding Activity of the Soluble Recombinant Pig Metallothionein 1A Expressed in Escherichia coli. Biological Trace Element Research. 2012, 150 (1-3): 418-423.
19. Generation of a mouse scFv library specific for porcine aminopeptidase N using the T7 phage display system. J Virol Methods. 2012, 182: 99-103.
20. Virus-binding activity of the truncated C subunit of porcine aminopeptidase N expressed in Escherichia coli. Biotechnol Lett. 2012, 34(3):533-9.
21. A polyclonal antibody against the C subunit of porcine aminopeptidase N expressed in Escherichia coli. Hybridoma (Larchmt). 2011, 30(5):457-62.
22. Development of a multiplex PCR for diagnosis of Staphylococcus aureus, Escherichia coli and Bacillus cereus from cows with endometritis. Agricultural Sciences in China, 2011, 10:1624-1629.
23. Combination of [i]D. nodosus[/i] LAMP with [i]F. necrophorum[/i] LAMP for detecting hoof swabs from dairy cattle footrot. African Journal of Microbiology Research, 2011, 5(6): 667-670.
24. Development of a novel LAMP diagnostic method for visible detection of swine Pasteurella multocida. Veterinary Research Communications, 2010, 34:649–657.
25. An Indirect ELISA for Serodiagnosis of Cattle Footrot Caused by Fusobacterium necrophorum. Anaerobe, 2010, 16(4):317-20
26. Identification of three immunodominant regions on leukotoxin protein of Fusobacterium necrophorum. Veterinary Research Communications, 2009, 33: 749-755. 二、著作、教材 1. 奶牛腐蹄病防治技术,中国农业出版社,2010年;
2. 奶牛乳房炎综合防治,中国农业出版社,2011年;
3. 兽医临床诊断学,黑龙江科学技术出版社,2010年;
4. 猪病科学防治7日通,中国农业出版社,2011年;
5. 羊病科学防治7日通,中国农业出版社,2012年;
6. 禽病防治技术,中国农业出版社,2012年;
7. 兽医临床诊断学,东北林业大学出版社,2014年。 三、专利 1. 猪传染性胃肠炎病毒单克隆抗体免疫生物制剂制备方法,第四名;
2. 猪流行性腹泻病毒弱毒疫苗株及其应用,第五名。
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