【个人简历】

2002年9月~2006年6月 北京服装学院 应用化学专业 本科

2006年9月~2011年6月 北京化工大学与清华大学联合培养 化学工程与技术专业 博士

2011年7月~2013年6月 清华大学深圳研究生院 分析化学专业 博士后

2013年8月至今 清华大学深圳研究生院 讲师

【研究领域】

研究方向为生命分析化学，主要从事微流控芯片及液质联用等技术在生命科学中的基础与应用研究，研究领域主要包括微流控芯片、代谢组学、蛋白质组学研究、药物分析等。获得了中国博士后科学基金的资助，承担了青年科学基金项目1项。

【论文与专利】

[1] Juntong Wei, Feng Jin, Qin Wu, Yuyang Jiang, Dan Gao*, Hongxia Liu*. Molecular Interaction Study of Flavonoid Derivative 3d with Human Serum Albumin Using Multispectroscopic and Molecular Modeling Approach. Talanta, doi: 10.1016/j.talanta.2014.03.046.

[2] Qin Wu1, Dan Gao1, Juntong Wei, Feng Jin, Weiyi Xie, Yuyang Jiang*, Hongxia Liu*. A novel multi-layer microfluidic device towards analysis of drug metabolism and cytotoxicity for high throughput drug screening. Chemical Communications, 50, 2762-2764, 2014. (1The two authors contributed equally to this work)

[3] Dan Gao, Feng Jin, Hongxia Liu*, Yini Wang, Yuyang Jiang*. Metabonomic study on the antitumor effect of flavonoid derivative 3d in HepG2 cells and its action mechanism. Talanta. 2014, 118, 382-388.

[4] Feng Jin1, Dan Gao1, Qin Wu, Feng Liu, Yuzong Chen, Chunyan Tan, Yuyang Jiang. Exploration ofN-(2-aminoethyl)piperidine-4-carboxamide as a potential scaffold for development of VEGFR-2, ERK-2 and Abl-1 multikinase inhibitor. Bioorganic & Medicinal Chemistry, 2013, 21, 5694–5706. (1The two authors contributed equally to this work)

[5] Xin Bi, Yibao Jin, Shangfu Li, Dan Gao*, Yuyang Jiang, Hongxia Liu*. Rapid and sensitive determination of fatty acids inedible oil by liquid chromatography–electrospray ionization tandem mass spectrometry. Science China Chemistry, 2013, doi: 10.1007s11426-013-4934-5.

[6] Xin Bi, Yibao Jin, Xiang Gao, Feng Liu, Dan Gao*, Yuyang Jiang, Hongxia Liu*. Investigation of Pokemon-regulated proteins in hepatocellular carcinoma using mass spectrometry-based multiplex quantitative proteomics. European Journal of Mass Spectrometry, 2013, 19(2), 111-121.

[7] Dan Gao, Hongxia Liu, Yuyang Jiang and Jin-Ming Lin*. Recent advances in microfluidics combinedwith mass spectrometry: technologies and applications. Lab on a Chip, 2013, 13, 3309-3322.

[8] Yini Wang1, Dan Gao1, Zhe Chen, Shangfu Li, Chunmei Gao, Deliang Cao, Feng Liu, Hongxia Liu*, Yuyang Jiang*. Acridone Derivative 8a Induces Oxidative Stress-Mediated Apoptosis in CCRF-CEM Leukemia Cells: Application of Metabolomics in Mechanistic Studies of Antitumor Agents, PLoS One, 2013, 8, e63572. (1The two authors contributed equally to this work)

[9] Dan Gao, Hongxia Liu, Jin-Ming Lin*, Yini Wang and Yuyang Jiang*. Characterization of drug permeability in Caco-2 monolayers by mass spectrometry on a membrane-based microfluidic device, Lab on a Chip, 2013, 13, 13, 978-985.

[10] Dan Gao, Hongxia Liu, Yuyang Jiang and Jin-Ming Lin*. Recent development of microfluidic devices in vitro cell culture for cell biology research, Trends in Analytical Chemistry, 2012, 35, 150–164.

[11] Dan Gao, Haifang Li, Niejun Wang, and Jin-Ming Lin*. Evaluation of the Absorption of Methotrexate on Cells and Its Cytotoxicity Assay by Using an Integrated Microfluidic Device Coupled to a Mass Spectrometer, Analytical Chemistry, 2012, 84, 9230-9237.

[12] Dan Gao, Huibin Wei, Guang-Sheng Guo, and Jin-Ming Lin*. Microfluidic Cell Culture and Metabolism Detection with Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometer, Analytical Chemistry, 2010, 82, 5679-5685.

[13] Dan Gao, Jiangjiang Liu, Hui-Bin Wei, Hai-Fang Li, Guang-Sheng Guo, Jin-Ming Lin*. A Microfluidic Approach for Anticancer Drug Analysis Based on Hydrogel Encapsulated Tumor Cells, Analytica Chimica Acta, 2010, 665, 7–14.

[14] Dan Gao, Hai-Fang Li, Guang-Sheng Guo, and Jin-Ming Lin*. Magnetic Bead Based Immunoassay for Enumeration of CD4+ T Lymphocytes on a Microfluidic Device, Talanta, 2010, 82, 528-533.

[15] Feng Jin, Dan Gao, Cunlong Zhang, Feng Liu, Bizhu Chu, Yan Chen, Yu Zong Chen, Chunyan Tan*, and Yuyang Jiang*. Exploration of 1-(3-chloro-4-(4-oxo-4H-chromen-2-yl)phenyl)-3-phenylurea derivatives as selective dual inhibitors of Raf1 and JNK1 kinases for anti-tumor treatment, Bioorganic & Medicinal Chemistry, 2012, 21, 824-831.

[16] Feng Jin, Nannan Zhang, Chunyan Tan, Dan Gao, Cunlong Zhang, Feng Liu, Zhe Chen, Chunmei Gao, Hongxia Liu, Shangfu Li, and Yuyang Jiang*. 2"-Chloro-4"-aminoflavone Derivatives Selectively Targeting Hepatocarcinoma Cells: Convenient Synthetic Process, G2/M Cell Cycle Arrest and Apoptosis Triggers, Archiv der Pharmazie, 2012, 345, 525-534.

[17] JiangJiang Liu, Dan Gao, SiFeng Mao, Jin-Ming Lin*. A microfluidic photolithography for controlled encapsulation of single cells inside hydrogel microstructures, Science China Chemistry, 2012, 55, 494-501.

[18] Sifeng Mao, Dan Gao, Wu Liu, Huibin Wei and Jin-Ming Lin*. Imitation of drug metabolism in human liver and cytotoxicity assay using a microfluidic device coupled to mass spectrometric detection, Lab on a Chip, 2012, 12, 219-226.

[19] Huibin Wei, Haifang Li, Dan Gao and Jin-Ming Lin*. Multi-channel Microfluidic Devices Combined with Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry Applied to the Monitoring of Glutamate Release from Neuronal Cells, Analyst, 2010, 135, 2043-2050.

[20] Chuansen Liu, Jiangjiang Liu, Dan Gao, Mingyu Ding and Jin-Ming Lin*. Fabrication of Microwell Arrays Based on Two-dimensional Ordered Polystyrene Microspheres for High-throughput Single-Cell Analysis, Analytical Chemistry, 2010, 82, 9418-9424.

[21] Jiangjiang Liu, Dan Gao, Hai-Fang Li and Jin-Ming Lin*. Controlled Photopolymerization of Hydrogel Microstructures inside Microchannels for Bioassays, Lab on a Chip, 2009, 9, 1301–1305.