导师陈红平
陈红平博士
南昌大学基础医学院组织胚胎学教研室主任
博士生导师
江西省杰出青年人才资助计划
美国波士顿大学医学院和托马斯杰斐逊大学医学院博士后
l 教育和工作背景:
2015/01-至今, 南昌大学,基础医学院,教授/博士生导师
2014/09-至今 南昌大学基础医学院组胚教研室主任、基础医学院教授委员会委员。
2009/01-2014/12, 南昌大学,基础医学院,副教授。
2011/03 -2013/03,美国托马斯杰斐逊医学院,药理和试验治疗系,博士后。
2010/06-2011/02,美国波士顿大学医学院,Roger Williams医学院,博士后。
2009/01-2010/05,美国托马斯杰斐逊医学院,药理和试验治疗系,博士后。
2006/07-2008/12,南昌大学,基础医学院,讲师。
2003/9 - 2006/6,中国农业大学,生理学,博士。
2000/9 - 2003/6,江西农业大学,基础兽医学,硕士。
1996/9 - 2000/6,江西农业大学,动物医学,学士
l 研究兴趣、领域:
现从事肾、心和肝等器官损伤保护、神经病理性疼痛、心肌细胞分化和癌症等方面的研究。近年来在Oncogene. Molecular Pain,和Experimental Neurology等杂志发表SCIE收录论文14篇。
l 代表性论文:
(1) Chen HP(陈红平), Jingjing Fan, Sheng Cui. Detection and estrogen regulation of leptin receptor expression in rat dorsal root ganglion. Histochemistry and cell biology, 126:363-369, 2006.
(2) Chen HP(陈红平), L Zhang, B H Xu, L M Kang, S L Yang, H H Zeng, X Y Shi. Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism. Cell and tissue, 41:133-140, 2009
(3) Chen HP(陈红平), Denicola M, Qin X, Zhao Y, Zhang L, Long XL, Zhuang S, Liu PY, Zhao TC. HDAC inhibition promotes cardiogenesis and the survival of embryonic stem cells through proteasome-dependent pathway.Journal of Cellular Biochemistry. 112(11):3246-3255,2011.
(4)Taccioli C, Chen H(陈红平), Jiang Y, Liu XP, Huang K, Smalley KJ, Farber JL, Croce CM, Fong LY*.Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature. Oncogene. 31(42):4550-4558,2012.(共同第一作者).
(5)Alder H, Taccioli C, Chen H(陈红平), Jiang Y, Smalley KJ, Fadda P, Ozer HG, Huebner K, Farber JL, Croce CM, Fong LY*. Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. Carcinogenesis. 33(9):1736-1744, 2012 (共同第一作者)
(6) Li X, Kang L, Li G, Zeng H, Zhang L, Ling X, Dong H, Liang S, Chen H(陈红平)*. Intrathecal leptin inhibits expression of the P2X2/3 receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury. Mol Pain. 9:65, 2013. (通讯作者)
(7)Chen HP(陈红平), Zhou W, Kang LM, Yan H, Zhang L, Xu BH, Cai WH*.Intrathecal miR-96 inhibits Nav1.3 expression and alleviates neuropathic pain in rat following chronic construction injury. Neurochemical Research.39:76-83, 2014.
(8)Chen HP(陈红平), Zhao YT, Zhao Ting C. Histone Deacetylases and Mechanisms of Regulation of Gene Expression. critical reviews in oncogenesis, 20:35-47, 2015.
(9)Chen H(陈红平), Wang Q, Lei, Q, Zhang, L, Kang L*. Ontogenic expression profiles and oxaliplatin regulation of leptin expression in mice dorsal root ganglion. Neuroreport 26: 870-876, 2015.
(10) Liu L, Xu K, Kang LM, Jiang SP, Wang QH, Zhang Lei, Wan SG, Chen HP(陈红平)*. Pholidota chinensis alleviates azoxymethane/dextran sulfate sodium-induced colorectal carcinogenesis through inhibition of TLR4 and COX-2. Afr J Tradit Complement Altern Med, 12(6):113-121, 2015, (通讯作者)
(11)Shu-Ping Jiang, Zhen-Dong Zhang, Lu-Mei Kang, Qing-Hua Wang, Lei Zhang , Hong-Ping Chen(陈红平). Celecoxib reverts oxaliplatin-induced neuropathic pain through inhibiting PI3K/Akt2 pathway in the mouse dorsal root ganglion. Experimental Neurology, 275:11-16,2016 (通讯作者)
(12)Hongping Chen(陈红平), Qinghua Wang , Danni Shi , Dongbo Yao , Lei Zhang, Junping Xiong , and Baohua Xu. Celecoxib alleviates oxaliplatin-induced hyperalgesia through inhibiting spinal ERK1/2 signaling. Journal of toxicologic pathology, 29: 253–259, 2016
(13)Chunhua Yin, Lumei Kang, Cong Lai, Jing Zhou, Bin Shi, Lei Zhang, and Hongping Chen(陈红平). Effects of 17β-estradiol on leptin signaling in anterior pituitary of ovariectomized rats. Exp. Anim. 66 (2), 159–166, 2017 (通讯作者)
(14)Xiang Ling, Dongbo Yao, Lumei Kang, Jing Zhou, Ying Zhou, Hui Dong, Keping Zhang, Lei Zhang, Hongping Chen(陈红平)#. Involment of RAS/ERK1/2 signaling and MEF2C in miR-155-3p inhibition-triggered cardiomyocyte differentiation of embryonic stem cell. Oncotarget, 8 (48): 84403-84416 , 2017 (通讯作者)
(15) Dan-Ni Shi, Yi-Tao Yuan, Dan Ye, Lu-Mei Kang, Jing Wen, Hong-Ping(陈红平#. ChenMiR-183-5p alleviates chronic constriction injury-induced neuropathic pain through inhibition of TREK-1. Neurochemical Research.43(6): 1143–1149. (通讯作者)
l 所获项目、荣誉、奖励及参加学术团体的情况:
1. 主持国家自然科学基金地区基金,项目批准号:81260318, TLR4在缺锌诱发的食管癌中的作用及其机理研究、2013/01/01-2016/12/31、55万元(已结题)。
2. 主持国家自然科学基金青年基金,项目批准号:30800424;瘦素在神经病理性疼痛中的作用及相关机理研究、2009/01/01-2011/12/30、20.0万(已结题)。
3. 主持人才团队计划-杰出青年人才资助计划(江西省),20171BCB23027,金额:15万元,2017.06-2020.06. 在研。
4. 主持国家自然科学基金,线粒体保护在瑞沙托维减轻奥沙利铂诱导的神经病理性疼痛中的作用,项目批准号:81760213;金额:34万,年限:2018.01-2021.12。
l 联系方式:
电话:13517091601
E-mail: jxchp2000@126.com