曾晓飞，男，教授，硕士研究生导师，浙江省高校中青年学科带头人。1983年5月生，江西吉安人。2003年本科毕业于南昌大学，2006年硕士毕业于苏州大学，2010 年博士毕业于新加坡南洋理工大学化学与生物化学系，师从著名有机化学家钟国富教授（长江学者、南洋理工大学化学与生物化学系创系教授之一），主要从事新型手性催化剂的设计、合成及不对称催化反应研究、药物合成研究。2011-2012年作为高级研究员就职于美国Albany新药研发公司新加坡分公司。同年获得德国洪堡学者奖学金并于2012年2月-2013年7月在德国亚琛工业大学有机化学研究所从事博士后研究工作，合作教授为世界著名有机化学家Dieter Enders教授。2013年11月起以特聘教授入职杭州师范大学至今，2016年12月晋升为教授。2014年获得德国Thieme杂志社颁发的Thieme Chemistry Journal Award；同年获得杭州市“西湖学者”称号；2017年被评为杭州市教育局系统优秀教师；是浙江省高校中青年学科带头人，杭州市“创新药物研究”重中之重实验室分方向负责人。主持了包括国家自然科学基金、浙江省自然科学基金、浙江省公益技术应用研究计划项目、杭州市留学回国人员创业创新项目等项目。近三年来，指导本科学生获得省级竞赛奖项2次、“国创”项目1项、新苗计划1项、省级优秀毕业论文1人。在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Org. Lett.、Chem. Commun.等国际一流杂志上发表SCI论文30余篇，多次被国际著名评论杂志Synfacts收录并作为亮点介绍。现为Angew. Chem. Int. Ed.、Chem. Commun.、Org. Biomol. Chem.、Curr. Org. Chem.等杂志特约审稿人。

电话：15157124399；邮箱：chemzxf@hznu.edu.cn; chemzxf@163.com

教育与学术经历:

1999.09-2003.07           南昌大学化学与材料科学学院 获学士 (B. Eng)学位

2003.09-2006.07           苏州大学化学化工学院 获硕士 (M.Eng)学位

2006.08-2010.07           新加坡南洋理工大学化学系 获理学博士 (Ph.D.)学位

2010.08-2011.01           新加坡南洋理工大学化学系 研究助理

2011.02-2012.01          美国Albany制药新加坡公司 高级研究员

2012.02-2013.07           德国亚琛工业大学有机化学研究所 博士后（洪堡学者）

2013.10-至今             杭州师范大学材料与化学化工学院 教授

荣誉和奖励:

2006 江苏省优秀硕士毕业论文

2011 AvH Humboldt Scholarship (洪堡学者奖学金)

2014 Thieme Chemistry Journal Award

2014 杭州市“西湖学者”

2017 杭州市教育局系统优秀教师

2017 浙江省高校中青年学科带头人

发表论文：（第一作者或通讯作者论文）

1.       TiCl4/DMAP mediated Z-selective knovenagel condensation of isatins with nitroacetates and related compounds, Zhu L.-Y.; Yan, P.-P.; Zhang, L.-Y.; Chen, Z.-T. Zeng, X.-F.; Zhong, G. RSC Adv. 2017, 7(81), 51352-51358.

2.       Construction of tetrahydropyranoquinoline derivatives via an asymmetric organocatalytic aza-Michael-IED/HAD cascade reaction, Dai.l.; Hou, Y.-X.; Zhang, L.-Y.; Chen, Z.-T.; Zeng, X.-F.; Zhong, G. Org. Biomol. Chem. 2017, 15(45), 9630-9637.

3.       Synthesis of Cyano-Containing Phenanthridine Derivatives via Catalyst-, Base-, and Oxidant-Free Direct Cyanoalkylarylation of Isocyanides Song, W.-H.; Yan, P.-P.; Shen, D.; Chen, Z.-T.; Zeng, X.-F.; Zhong, G. J. Org. Chem. 2017, 82(8), 4444-4448.

4.       A highly enantioselective Friedel-Crafts reaction of 3,5-dimethoxylphenol with nitroolefins mediated by a bifunctional quinine derived thiourea catalyst Han, X.-Y.; Ye. C.; Chen. F.-F.; Chen, Q.; Wang, Y.-J.; Zeng, X.-F. Org. Biomol. Chem. 2017, 15(16), 3401-3407.

5.       Enantioselective Dearomatization of Naphthol Derivatives with Allylic Alcohols by Cooperative Iridium and Bronsted Acid Catalysis Shen, D.; Chen, Q.-L.; Yan, P.-P.; Zeng, X.-F.; Zhong, G. Angew. Chem. Int. Ed. 2017, 56(12), 3242-3246.

6.       N-Heterocyclic Carbene/Lewis Acid Catalyzed Enantioselective Aerobic Annulation of α,β-Unsaturated Aldehydes with 1,3-Dicarbonyl Compounds Xie. D.-B.; Shen, D.; Chen, Q.-L.; Zhou, J.-Q.; Zeng, X.-F.; Zhong, G. J. Org. Chem. 2016, 81(14), 6136-6141.

7.       Enantioselective Construction of Spirocyclic Oxindole Derivatives with Multiple Stereocenters via an Organocatalytic Michael/Aldol/Hemiacetalization Cascade Reaction Zhu, L.-Y.; Chen, Q.-L.; Shen, D.; Zhang, W.-H.; Shen, C.; Zeng, X.-F.; Zhong, G. Org. Lett. 2016, 18(10), 2387.2390.

8.       Assembly of Enantioenriched cis-3a,8a-Hexahydropyrrolo[2,3-b]indole Scaffolds by Silver(I)-Catalyzed Asymmetric Domino Reaction of Isocyanoacetates in the Presence of Cinchona-Derived Chiral Phosphorus Ligands Cheng, H.-G.; Zhang, R.-M.; Yang, S.-W.; Wang, M.; Zeng, X.-F.; Xie, L.-J.; Xie, C.-S.; Wu, J. Zhong, G. Adv. Synth. Catal. 2016, 358(6), 970-976.

9.       Highly Enantio- and Diastereoselective L-Proline Derived Acetylglucose Amide Catalyzed Aldol Reaction of Ketones to Aldehydes under Solvent-Free Conditions Han, X.-Y.; Wang, Y.-J.; Gai, X.-K.; Zeng, X.-F. Synlett 2015, 26(20), 2858-2862.

10.     N-Heterocyclic Carbene-Catalyzed Activation of Esters of N-Hydroxyphthalimide: A Highly Enantioselective Route to Chiral Dihydropyridinones Bearing an All Carbon Quaternary Stereogenic Center Zhang, Z.-M.; Zeng, X.-F.; Xie, D.-B.; Chen, D.-D.; Ding, L.-Y.; Wang, A.-N.; Yang, L.-M.; Zhong, G. Org. Lett. 2015, 17(20), 5052-5055.

11.     Synthesis of 3-Oxazolines via SnCl4-Promoted Formal [3+2] Cycloaddition of Donor-Acceptor Oxiranes and Nitriles Zhou, H.; Zeng, X.-F.; Xie, Y.; Zhong, G. Synlett 2015, 26(12), 1693-1696.

12.     Triflic Acid Catalyzed Formal [3 + 2] Cycloaddition of Donor-Acceptor Oxiranes and Nitriles: A Facile Access to 3-Oxazolines Zhou, H.; Zeng, X.-F.; Ding, L.-Y.; Xie, Y.; Zhong, G. Org. Lett. 2015, 17(10), 2385-2387.

13.     Rapid Access to Spirocylic Oxindoles: Application of Asymmetric N-Heterocyclic Carbene-Catalyzed [3 + 3] Cycloaddition of Imines to Oxindole-Derived Enals Xie, D.-B.; Yang, L.-M.; Lin, Y.-Q.; Zhang, Z.-M.; Chen, D.-D.; Zeng, X.-F.; Zhong, G. Org. Lett. 2015, 17(10), 2318-2321.

14.     A Branched Domino Reaction: Asymmetric Organocatalytic Two-Component Four-Step Synthesis of Polyfunctionalized Cyclohexene Derivatives Zeng, X.-F.; Ni. Q.-J.; Raabe, G.; Enders, D. Angew. Chem. Int. Ed. 2013, 52(10), 2977-2980.

15.     Chiral Bronsted Acid Catalyzed Enantioselective Addition of α-Isocyanoacetamides to Aldehydes Zeng, X.-F.; Ye. K.-H.; Lu, M.; Chua, P. J.; Tan, B.; Zhong, G. Org. Lett. 2010, 12(10), 2414-2417.

16.     Highly Efficient Asymmetric Trans-Selective Aziridination of Diazoacetamides and N-Boc-imines Catalyzed by Chiral Bronsted Acids Zeng, X.-F.; Zeng, X.; Xu, Z.-J.; Lu, M.; Zhong, G. Org. Lett. 2009, 11(14), 3036-3039.

17.     Prolinol sulfinyl ester derivatives: organocatalytic Michael addition of ketones to nitroolefins under neat conditions Zeng, X.-F.; Zhong, G. Synthesis 2009, 9, 1545-1550.

18.     Facile synthesis of symmetrical triindolylmethanes catalyzed by iodine under solvent-free condition Zeng, X.-F.; Ji. S.-J.; Su. X.-M. Chin. J. Chem. 2008, 26(3), 413-416.

19.     Conjugate addition of indoles to α,β-unsaturated ketones (chalcones) catalyzed by KHSO4 under ultrasonic conditions Zeng, X.-F.; Ji. S.-J.; Shen, S.-S.; Chin. J. Chem. 2007, 25(12), 1777-1780.

20.     An efficient synthesis of bis(indolyl)methanes (BIAs) catalyzed by a recyclable solid superacid SO42-/TiO2 under solvent-free condition Zeng, X.-F.; Ji. S.-J. Lett. Org. Chem. 2006, 3(5), 374-378.

21.     Novel method for synthesis of unsymmetrical bis(indolyl)alkanes catalyzed by ceric ammonium nitrate (CAN) under ultrasonic irradiation Zeng, X.-F.; Ji. S.-J.; Wang, S.-Y. Tetrahedron 2005, 61(43), 10235-10241.

科研项目